MLB player prop bets and odds for Carlos Santana on Tuesday, July 22, 2025, as the Cleveland Guardians take on the Baltimore Orioles.

Jun 11, 2025; Cleveland, Ohio, USA; Cleveland Guardians relief pitcher Emmanuel Clase, middle, celebrates with first baseman Carlos Santana, left, after the Guardians beat the Cincinnati Reds at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images / Ken Blaze-Imagn Images

On July 21, 2025, the Cleveland Guardians defeated the Baltimore Orioles 10-5 at Progressive Field, improving their record to 49-50 and holding second place in the AL Central. The Orioles, now 44-55,

MLB player prop bets and odds for Carlos Santana on Sunday, July 20, 2025, as the Cleveland Guardians take on the Athletics.

"The Guardians could seek a taker for impending free agents such as Carlos Santana or Lane Thomas," Meisel writes, "If the Guardians move Santana at the deadline, that would clear a spot for Kayfus, who has earned a look."

José Ramírez, Bo Naylor and Kyle Manzardo go deep as the Guardians extend their streak to 11 straight games with a home run.

The Cleveland Guardians have had many notable players suit up and perform at the highest level, with Carlos Santana being no exception. After belting his 227th home run with the Guardians on Friday, he deserves to cap off his career in The Land.

Carlos Santana hit a tiebreaking two-run homer in the sixth inning, and the Cleveland Guardians beat the Chicago White Sox 4-2 in the opener of a split doubleheader.

Carlos Santana has been through this before. In fact, he’s been through it several times. The Guardians went into Monday night’s game against Houston on a 10-game losing streak. They’re 15 1/2 games out of first place in the AL Central and have just about drifted over the horizon in the wild-card chase.

Kyle Manzardo slugged his 16th home run of the year. And, as a reward, he was pinch-hit for with the bases loaded. That's the wrong call.